INHIBITION OF BACTERIAL GROWTH BY LEUCINE PEPTIDES
نویسندگان
چکیده
منابع مشابه
Inhibition of bacterial growth by leucine peptides.
In previous reports (I, 2), data were presented on the growth response of a leucineless mutant (strain 679-680)’ of Escherichia coli strain K-12 to various L-leucine peptides. Measurement of the extent of bacterial growth after 24 hours incubation showed that, at low concentrations, the peptides were almost as effective in the stimulation of growth as was L-leucine; at high concentrations, howe...
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The present study was undertaken as one approach to an elucidation of the effective structure of the antibiotic, gramicidin (1). The results of investigations of this sort are expected to lead to improved antibiotics, and to experimental approaches to the paths of biological synthesis of ,protein. A striking feature of gramicidin is its content of d-amino acids, notably d-leucine (2). The prese...
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Many integrins mediate cell attachment to the extracellular matrix by recognizing short tripeptide sequences such as arginine-glycine-aspartic acid and leucine-aspartate-valine. Using phage display, we have now found that the leukocyte-specific beta(2) integrins bind sequences containing a leucine-leucine-glycine (LLG) tripeptide motif. An LLG motif is present on intercellular adhesion molecule...
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Lactobacillus casei grows in the absence of vitamin Ba, provided that D-alanine and an unidentified peptide are added to a medium complete in other nutrients (1, 2). A partial hydrolysate of protein contained several chromatographically distinct fractions that possessed this “peptide factor” activity (3). It appeared likely that a single amino acid linked in a variety of combinations was respon...
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1 Generously provided by the Win. S. Merrell involved. Since casein hydrolyzate showed conCompany under their trade name of Meratran. siderable activity, and since the activity of It is [a-(2-piperidyl) benzhydrol] hydrochloride, a yeast extract was destroyed by nitrous acid and central stimulant, and is water-soluble and therto some extent by 1 N NaOH, but not by 1 N mostable. HCI, it seemed p...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1951
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56166-4